EPIDEMIOLOGIC DATA, PROGNOSIS AND ETIOPATOGENY IN CHRONIC COR PULMONALE COPD RELATED
Abstract:
Cor pulmonale represents an important complication of chronic obstructive pulmonary disease (COPD), because it is responsabile for a large number of hospitalizations for heart faillure. The development of pulmonary arterial hYpertension (PAH) influences the prognosis of persons with COPD. PAH is the primary cardiovascular complication encountered in chronic obstructive pulmonary disease. The prevalence of PAH increases as COPD worsens, and the development of PAH and cor pulmonale appears to affect survival of patients with COPD. Potential causes proposed to explain the development of PAH in COPD include gas exchange abnormalities, destruction of the pulmonary vascular bed, alterations in respiratory mechanics, changes in intrinsic pulmonary vessel tone, and increased blood viscosity. The goal is the early detection of PAH which complicate COPD and so proper therapy can be established.
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