THE ROLE OF VITAMIN D, OBESITY, PHYSICAL EXERCISE, SLEEPING AND QUALITY OF LIFE IN REGULATION OF BLOOD PRESSURE
Abstract:
The aim of the study is to evaluate the effect of lifestyle modification, nutritional and mental
behaviours, physical activity, weight, sleeping, fasting, blood sugar, vitamin D and the biochemistry
profile among hypertensive patients. Materials and methods: This cross-sectional study was based on
1154 subjects. Data analysis included sociodemographics, life-style habits, anthropometric, body
mass index (BMI), hypertensions, clinical biochemistry, systolic and diastolic blood pressure,
Pittsburgh Sleep Quality Index (PSQI) and quality of life questionnaire. Univariate and multivariate
statistical analyses were performed. Results: Out of 1154 subjects, 528 (45.8%) were males and 626
(54.2%) were females. There were statistically significant differences between uncontrolled
hypertensive and well-controlled hypertensive patients regarding; gender, educational level,
household income, BMI, smoking habits, alcohol use, physical exercise, sport activity, co-morbid
complications, associated symptoms, hypertension treatment mode, PSQI, vitamin D, blood glucose,
HbA1c level, calcium, urea, bilirubin, and systolic and diastolic blood pressures, hours of sleeping
and BMI respectively. The principal component extraction, promax rotation indicated that total
variances explained was 73.8%, Cronbach’s alpha 0.81, KMO value was 0.70 and significant with
p<0.001. The correlation between the factors was high: r=0.467 and p<0.001. Multivariate stepwise
regression predicted that systolic (mmHg) (p<0.001) and diastolic blood pressure (mmHg) (p<0.001),
HbA1c (p<0.001), lack of physical exercise (p<0.001), vitamin D deficiency (p<0.001), quality of life
(p=0.029), social relationship (p=0.033), sleeping (p=0.049) were identified as statistically
significant risk factor for hypertensive. Conclusion: The present study determines lifestyle
modification with vitamin D supplement, diet, regular physical exercise and sleeping can substantially
lower blood pressure and improve blood pressure control of hypertensive patients
full text article in English (.EN) |