LINKS BETWEEN OBESITY, SELENIUM SUPPLEMENTATION, AND TITRE OF THYROID PEROXIDASE ANTIBODIES
Abstract:
Introduction: Evaluation of the influence of administration of selenium supplements over a period of 6 months on the evolution of titers of anti-thyroid peroxidase antibodies in patients with chronic autoimmune thyroiditis. Materials and methods: We monitored data collected from the archive of Endocrinology Ambulatory in Târnăveni city, for a group of 109 female patients with newly diagnosed chronic autoimmune thyroiditis, with or without impairment of thyroid hormone status. Results: Our study confirms that selenium supplementation at a dose of 200 micrograms per day over a 6-month period resulted in a significant decrease in serum levels of anti-thyroid peroxidase antibodies. The titer of anti-thyroid peroxidase antibodies at 6 months of selenium supplementation, decreased to 85.3% of the investigated patients, with 26.31% of the initial value. Conclusions: Selenium has proven effective in chronic autoimmune thyroiditis in order to maintain a balance of autoimmune thyroid disease.
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