ASSESSMENT OF FETAL WEIGHT COMING FROM PREGNANCIES OBTAINED BY IN VITRO FERTILIZATION - CASE CONTROL STUDY
Abstract:
One of the most discussed topics in the current literature is the influence of human assisted
reproductive techniques (ART ) on fetal growth. Numerous studies have been conducted to determine
the factors that influence the fetal weight of newborns achieved through ART. It has come to the
theory that the weight of newborns obtained by ART is influenced by several factors: the expression of
genes influenced by ovarian stimulation, the impact on genome expression at the endometrial level,
placental development and placental weight, complications of pregnancy, age of sterility, and ART
indications. The aim of the study is to assess the weight of IVF newborns. We also evaluated the
delivery path, the presentation and other associated pathologies of the fetuses. We conducted a
statistical, retrospective and comparative study. The study was conducted on a group of 106 patients
from pregnancies obtained by in vitro fertilization (IVF).The study included patients from the
Emergency County Clinical Hospital of Sibiu, Obstetrics and Gynecology Clinic from January 2010
to December 2016. The IVF group was compared to a control group of 212 patients. Concidering the
small number of cases we selected two witnesses for each patient. Depending on gestational age, birth
weight, waist, cranial perimeter, weight index, Apgar score at 1 minute, physiological weight loss and
duration of hospitalization - there were no differences with statistical significance between the two
groups. In the IVF group 63.2% of the patients were female compared to the control group where only
44.3% of the patients were female. There are no significant differences in the weight of the patients
between the IVF group and the control group.The weight ratio of newborns within the IVF group has
a value close to that of newborns in the control group. There are no statistical differences between the
IVF group and the control group regarding waist and cranial perimeter.
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