A RARE GIANT CELL TUMOUR OF THE SACRUM: CASE REPORT
Abstract:
The current report describes the case a 41 year-old female with a sacral giant cell tumour.
The patient presented with low-back pain that radiated to the both lower limbs. Magnetic Resonance
Imaging (MRI) revealed a huge tumour mass (110×120 mm in size) involving the sacrococcygeal region
between S1 and S5 with invasion of the vertebral bodies at this level, with possible posterior extensions
of the spinal canal between S1 and S3. The patient was treated surgically on 10th June 2014. The tumour
was subtotal resected. Histopathological examination of removed mass confirmed the diagnosis of giant
cell tumor. The patient underwent radiotherapy and an adjuvant treatment with bisphosphonate
zoledronic acid from October 2014 until now. After surgery and adjuvant treatment with zolendronic
acid, the patient had reduced on intensity back pain, she was able to walk with a cane and had control of
the urinary bladder and anal sphincter. Conclusions: Giant cell tumour of the bone is a rare tumour that
can be locally aggressive. Radical surgical removal is the optimal treatment. Radiotherapy is preferred
for a subtotal resection. Adjuvant treatment with zolendronic acid or denosumab has been reported to be
effective and safe.
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