CORRELATIONS BETWEEN PRECANCEROUS LESIONS AND MELANOCYTIC AND NON-MELANOCYTIC SKIN CANCERS
Abstract:
Nonmelanocytic skin cancers (NMSC) are the most common frequent of skin cancers, which
may appear de novo, in normal skin or on precancerous cutaneous lesions. There are many pre-existing
lesions holding a potential to transform in skin cancers. Of these, the most common are actinic and
seborrheic keratoses, sebaceous nevus, leukoplakia etc. Malignant melanoma (MM) can appear after a
malignant transformation of melanocytic lesions or of nevi with a dysplastic potential or de novo in
apparently healthy skin. Lately, the medical community has observed more frequent de novo MM than
the ones building upon underlying nevi lesions. Based on these data and taking into account that the
diagnosis and treatment of precancerous lesions would allow reducing the incidence of skin
malignancies and thus mortality, especially in MSC, we conducted a prospective study in which we
analyzed precancerous lesions and the NMSC and MSC that appeared on these
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