NT- PRO BNP, IMPORTANT MARKER FOR EVOLUTION. MONITORING ACUTE CORONARY SYNDROMESWITH NO ST INCREASE
Abstract:
Brain natriuretic peptide (BNP), a neurohormone peptide synthesized in ventricular
myocardium and effused into circulation in response to ventricular dilatation and pressure overload,
leading to an increase in natriuresis, vasodilatation, inhibition of angiotensin-aldosterone axis and
sympathetic activity, becomes elevated in heart failure. It is possible to differentiate it by dosing
inspiratory dyspnea due to cardiac infarction normal ejection fraction (EF) without left ventricular (LV)
dysfunction. BNP superior to a prohormone ANP is then cleaved at the N-terminus to produce the BNP
peptide and N-terminal proBNP (NT-proBNP). This hormone has been incriminated as present in the
acute coronary syndromes with ST which increased in the first 24 hours after myocardial infraction
(MI).
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